Vancomycin hypersensitivity
نویسندگان
چکیده
RED MAN SYNDROME — The most common adverse reaction to vancomycin is "red man syndrome" (RMS), which also may be called "red neck syndrome." RMS is not thought to involve drug-specific antibodies and may develop even with the first administration of vancomycin. RMS is a form of pseudoallergic drug reaction, or an adverse drug reactions with signs and symptoms that mimic immunologic drug allergies, but in which immunologic mechanisms have not be demonstrated.
منابع مشابه
Desensitization protocols for vancomycin hypersensitivity.
OBJECTIVE To discuss the pathophysiology of vancomycin-induced immediate hypersensitivity reactions, review the process of vancomycin desensitization, and provide specific directions for ordering and preparing rapid and slow desensitization protocols. DATA SOURCES A MEDLINE search (1966-February 2001) of English-language literature pertaining to vancomycin desensitization and hypersensitivity...
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Intraperitoneal (IP) vancomycin is widely used to treat Gram-positive peritonitis associated with peritoneal dialysis. There have been two cases of red man syndrome (RMS), a vancomycin-specific nonimmunologic reaction, associated with IP vancomycin. However, immune-mediated hypersensitivity reaction to IP vancomycin has not yet been reported. A 49 year old woman on continuous ambulatory periton...
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Drug hypersensitivity syndrome to both vancomycin and teicoplanin has not been previously reported. We describe here a 50-yr-old male patient with vertebral osteomyelitis and epidural abscess who developed hypersensitivity syndrome to both vancomycin and teicoplanin. Skin rash, fever, eosinophilia, interstitial pneumonitis, and interstitial nephritis developed following the administration of ea...
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